Overview

Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment 4‑7. To improve metabolic stability and receptor selectivity, researchers substituted specific amino acids and added a C‑terminal Pro‑Gly‑Pro extension, producing a peptide with enhanced resistance to enzymatic degradation and improved bioavailability【351314047742813†L51-L60】. In experimental studies, Semax has been shown to up‑regulate brain‑derived neurotrophic factor (BDNF) and its receptor TrkB, modulate dopaminergic and serotonergic neurotransmission, and exert neuroprotective effects after hypoxic or ischemic injury【351314047742813†L75-L84】. This synthetic analog is supplied as a lyophilized powder and is intended strictly for laboratory and analytical use.

Key Research Applications

– **Neuroprotection and recovery:** Evaluate Semax’s ability to protect neurons from hypoxic/ischemic damage and to promote functional recovery via BDNF/TrkB signaling and anti‑apoptotic pathways【351314047742813†L75-L84】.
– **Cognitive performance and memory:** Investigate how Semax influences cognitive function, learning, and memory through modulation of neurotransmitter release and synaptic plasticity【351314047742813†L75-L84】.
– **Stress and mood regulation:** Explore the peptide’s effects on stress responses, anxiety‑like behavior, and mood via interactions with monoaminergic systems.
– **Ophthalmology and retinal health:** Examine Semax’s potential to protect retinal ganglion cells and maintain visual function in models of optic nerve injury.
– **Mechanistic studies:** Dissect receptor binding, signal transduction, gene expression, and downstream molecular targets to elucidate how Semax exerts its neuroprotective and neuromodulatory effects.

Quality & Handling

– Supplied as a sterile, lyophilized powder in 10 mg vials for precise dosing.
– Reconstitute with bacteriostatic water or an appropriate buffer before use; use aseptic techniques.
– Once reconstituted, aliquot and store at 2–8 °C for short‑term use; freeze at –20 °C for long‑term storage to maintain peptide integrity.
– Avoid repeated freeze‑thaw cycles and exposure to strong light or heat.

Important Notice

This material is sold for **research purposes only**. It is not intended for human or veterinary use, nor for diagnostic or therapeutic applications. All purchasers must be qualified researchers or licensed professionals familiar with appropriate handling of synthetic peptides.

Why Choose Anytime Compounds?

Anytime Compounds provides high‑purity research peptides manufactured under strict cGMP conditions and tested by independent third‑party laboratories for identity and purity. We offer responsive customer service, competitive pricing, and same‑day shipping to researchers across the United States and Canada. Choose our Semax to ensure consistency and reliability in your experiments.