**Overview**
TB-500 is a synthetic derivative of thymosin β4, a naturally occurring 43‑amino‑acid peptide widely expressed in mammalian tissues【594934410668676†L172-L181】. Thymosin β4 functions as a major actin-sequestering protein that modulates cell migration, angiogenesis, inflammation and wound repair. TB‑500 comprises the bioactive central region of thymosin β4 and retains its ability to enhance tissue regeneration, stimulate angiogenesis and cell proliferation and suppress pro‑inflammatory cytokines.
**Key Research Applications**
– Investigating mechanisms of angiogenesis and endothelial cell migration in models of cardiac repair, ischemia and tissue regeneration.
– Studying wound healing, collagen deposition and extracellular matrix remodelling in skin, tendon and ligament injury models.
– Exploring anti-inflammatory pathways and apoptosis inhibition mediated by thymosin β4 fragments.
– Evaluating TB‑500’s potential in fibrotic disease models (cardiac, liver or renal fibrosis) and ulcerative colitis.
– Examining interactions with growth factors (e.g., VEGF, FGF) and cytoskeletal proteins that regulate cell motility and differentiation.
**Quality & Handling**
– Supplied as a high-purity lyophilised peptide.
– Reconstitute with sterile water or buffer; gently swirl to dissolve.
– Aliquot and store at – 20 °C; avoid repeated freeze–thaw cycles.
– For laboratory research use only; not intended for therapeutic or veterinary applications.
**Important Notice**
TB‑500 is provided strictly for research and development. It is not approved for human or veterinary use, diagnostic procedures or treatment.
**Why Choose Anytime Compounds?**
Our peptides are synthesised to GMP standards and tested by independent laboratories. TB‑500 batches are accompanied by COA and endotoxin data to verify purity and identity. We deliver reliable quality, competitive pricing and prompt shipment to support your research.




